Getzar Plus Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing Brand Resources

Concise Prescribing Info

Contents

Per 50 mg/12.5 mg FC tab Losartan K 50 mg, hydrochlorothiazide 12.5 mg. Per 100 mg/25 mg FC tab Losartan K 100 mg, hydrochlorothiazide 25 mg

Indications/Uses

HTN including patients w/ left ventricular hypertrophy; diabetic nephropathy in type 2 DM.

Click to view Getzar Plus detailed prescribing information

Dosage/Direction for Use

Usual dose: 50 mg/12.5 mg once daily, may be increased to 100 mg/25 mg daily as a single dose or in 2 divided doses. Elderly >75 yr, patient w/ moderate to severe renal impairment (CrCl <20 mL/min) or intravascular fluid depletion Initially 25 mg once daily.

Click to view Getzar Plus detailed prescribing information

Overdosage

View Getzar Plus overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food.

Contraindications

Severe renal impairment (CrCl <30 mL/min) or anuria, Addison's disease, preexisting hypercalcemia. Pregnancy.

Click to view Getzar Plus detailed prescribing information

Special Precautions

Renal artery stenosis/impairment. Monitor fluid & electrolyte imbalance especially in the presence of vomiting or during parenteral fluid therapy.

Click to view Getzar Plus detailed prescribing information

Use In Pregnancy & Lactation

Click to view Getzar Plus detailed prescribing information

Adverse Reactions

Losartan K: Dizziness & dose-related orthostatic hypotension; hyperkalemia. Hydrochlorothiazide: Metabolic disturbances at high dose; hyperglycemia & glycosuria; hyperuricemia & gout-precipitated attacks; electrolyte imbalances including hypochloremic alkalosis, hyponatremia & hypokalemia.

Click to view Getzar Plus detailed prescribing information

Drug Interactions

Losartan K: Rifampicin & fluconazole; K-sparing diuretics, K supplements or K-containing salt substitutes. Hydrochlorothiazide: Alcohol, barbiturates or narcotics; antidiabetic drugs (oral agents & insulin); other antihypertensive drugs; cholestyramine & colestipol resins; corticosteroids, ACTH; pressor amines (eg, adrenaline).

Click to view Getzar Plus detailed prescribing information

Storage

View Getzar Plus storage conditions for details to ensure optimal shelf-life.

Description

View Getzar Plus description for details of the chemical structure and excipients (inactive components).

Action

View Getzar Plus mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Angiotensin II Antagonists / Diuretics

ATC Classification

C09DA01 - losartan and diuretics ; Belongs to the class of angiotensin II receptor blockers (ARBs) in combination with diuretics. Used in the treatment of cardiovascular disease.

Regulatory Classification

Presentation/Packing

Form

Getzar Plus 100 mg/25 mg FC tab

Packing/Price

100's (P3,025/box)

Form

Getzar Plus 50 mg/12.5 mg FC tab

Packing/Price

50's (P1,134.38/box)

Getzar Plus

losartan + hydrochlorothiazide

Manufacturer:

Hizon

Distributor:

Getz Pharma